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Our lab is interested in RNA regulatory mechanisms — from discovery to application.
Our lab is interested in RNA regulatory mechanisms — from discovery to application.
We explore the diverse strategies that viruses use to control RNA, and we translate these mechanisms into improved RNA therapeutic platforms.
We explore the diverse strategies that viruses use to control RNA, and we translate these mechanisms into improved RNA therapeutic platforms.
- Viral RNA Regulatory Mechanisms
We study viruses as a rich reservoir of RNA regulatory mechanisms. Because viruses must hijack the host's cellular machinery and redirect it for their own benefit, they have evolved diverse and often elegant strategies to control RNA. By studying these strategies, we aim to uncover previously unrecognized RNA regulatory mechanisms, combining computational analysis with experimental approaches. (Link)
- RNA Therapeutics
We are interested in the full range of RNA therapeutic platforms, including mRNA and self-amplifying RNA (saRNA). We aim to harness viral elements that enhance gene expression to improve current RNA therapeutics. (Link) Our ultimate goal is to propose novel RNA platforms by studying viral regulatory mechanisms and applying them to therapeutic design.
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